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Identification of a New Cholesterol‐Binding Site within the IFN‐γ Receptor that is Required for Signal Transduction

The cytokine interferon‐gamma (IFN‐γ) is a master regulator of innate and adaptive immunity involved in a broad array of human diseases that range from atherosclerosis to cancer. IFN‐γ exerts it signaling action by binding to a specific cell surface receptor, the IFN‐γ receptor (IFN‐γR), whose activ...

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Detalles Bibliográficos
Autores principales: Morana, Ornella, Nieto‐Garai, Jon Ander, Björkholm, Patrik, Bernardino de la Serna, Jorge, Terrones, Oihana, Arboleya, Aroa, Ciceri, Dalila, Rojo‐Bartolomé, Iratxe, Blouin, Cédric M., Lamaze, Christophe, Lorizate, Maier, Contreras, Francesc‐Xabier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9008429/
https://www.ncbi.nlm.nih.gov/pubmed/35166455
http://dx.doi.org/10.1002/advs.202105170