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Expression of chronic myeloid leukemia oncogenes BCR-ABL (P210) and BCR-ABL (T315I) affect cellular and humoral innate immunity in Drosophila melanogaster

Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm that results from a chromosomal translocation between chromosome 9 and chromosome 22. The resulting fusion gene ( BCR-ABL ) encodes a constitutively active BCR-ABL tyrosine kinase. Some mutations of this oncogene, especially the Threoni...

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Detalles Bibliográficos
Autores principales: Abubaker, Dana, Baassiri, Amro, Ghannam, Mirna, Al Outa, Amani, Ghais, Ali, Rahal, Elias, Nasr, Rihab, Shirinian, Margret
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9008464/
https://www.ncbi.nlm.nih.gov/pubmed/35622506
http://dx.doi.org/10.17912/micropub.biology.000551