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FNIP1 regulates adipocyte browning and systemic glucose homeostasis in mice by shaping intracellular calcium dynamics

Metabolically beneficial beige adipocytes offer tremendous potential to combat metabolic diseases. The folliculin interacting protein 1 (FNIP1) is implicated in controlling cellular metabolism via AMPK and mTORC1. However, whether and how FNIP1 regulates adipocyte browning is unclear. Here, we demon...

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Detalles Bibliográficos
Autores principales: Yin, Yujing, Xu, Dengqiu, Mao, Yan, Xiao, Liwei, Sun, Zongchao, Liu, Jing, Zhou, Danxia, Xu, Zhisheng, Liu, Lin, Fu, Tingting, Ding, Chenyun, Guo, Qiqi, Sun, Wanping, Zhou, Zheng, Yang, Likun, Jia, Yuhuan, Chen, Xinyi, Gan, Zhenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9008465/
https://www.ncbi.nlm.nih.gov/pubmed/35412553
http://dx.doi.org/10.1084/jem.20212491