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Role of Cytokines in Thymic Regulatory T Cell Generation: Overview and Updates

CD4(+)CD25(+)Foxp3(+) Regulatory (Treg) T cells are mainly generated within the thymus. However, the mechanism of thymic Treg cell (tTreg cell) generation remains to be fully revealed. Although the functions of TCR/CD28 co-stimulation have been widely accepted, the functions of cytokines in the gene...

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Detalles Bibliográficos
Autores principales: Tang, Mei, Jia, Fuya, Nan, Fang, Zuo, Fengqiong, Yuan, Zhu, Zhang, Dunfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9008509/
https://www.ncbi.nlm.nih.gov/pubmed/35432378
http://dx.doi.org/10.3389/fimmu.2022.883560