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Chains or rings? Polymorphism of an isoniazid derivative derivatized with diacetone alcohol

Isoniazid was derivated with diacetone alcohol in a Schiff-base reaction in order to yield N′-[(2E)-4-hydroxy-4-methylpentan-2-ylidene]pyridine-4-carbohydrazide. The resulting product was determined to be polymorphic, exhibiting two crystal forms: form I and form II. From the crystal structure deter...

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Detalles Bibliográficos
Autores principales: Scheepers, Matthew C., Fernandes, Manuel A., Lemmerer, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9008515/
https://www.ncbi.nlm.nih.gov/pubmed/35432943
http://dx.doi.org/10.1039/d2ra02057b