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QCL–IR Spectroscopy for In-Line Monitoring of Proteins from Preparative Ion-Exchange Chromatography

[Image: see text] In this study, an external cavity-quantum cascade laser-based mid-infrared (IR) spectrometer was applied for in-line monitoring of proteins from preparative ion-exchange chromatography. The large optical path length of 25 μm allowed for robust spectra acquisition in the broad tunin...

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Detalles Bibliográficos
Autores principales: Akhgar, Christopher K., Ebner, Julian, Spadiut, Oliver, Schwaighofer, Andreas, Lendl, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9008697/
https://www.ncbi.nlm.nih.gov/pubmed/35353485
http://dx.doi.org/10.1021/acs.analchem.1c05191