β-micrustoxin (Mlx-9), a PLA(2) from Micrurus lemniscatus snake venom: biochemical characterization and anti-proliferative effect mediated by p53

BACKGROUND: Endogenous phospholipases A(2) (PLA(2)) play a fundamental role in inflammation, neurodegenerative diseases, apoptosis and cellular senescence. Neurotoxins with PLA(2) activity are found in snake venoms from the Elapidae and Viperidae families. The mechanism of action of these neurotoxin...

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Detalles Bibliográficos
Autores principales: dos Santos, Natália Fernanda Teixeira, Imberg, Andréia de Souza, Mariano, Douglas Oscar Ceolin, de Moraes, Angelina Cirelli, Andrade-Silva, Jessica, Fernandes, Cristina Maria, Sobral, Ana Cláudia, Giannotti, Karina Cristina, Kuwabara, Wilson M. Tatagiba, Pimenta, Daniel Carvalho, Maria, Durvanei Augusto, Sandoval, Maria Regina Lopes, Afeche, Solange Castro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centro de Estudos de Venenos e Animais Peçonhentos (CEVAP/UNESP) 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9008913/
https://www.ncbi.nlm.nih.gov/pubmed/35432496
http://dx.doi.org/10.1590/1678-9199-JVATITD-2021-0094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9008913/
https://www.ncbi.nlm.nih.gov/pubmed/35432496
http://dx.doi.org/10.1590/1678-9199-JVATITD-2021-0094

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