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Delineating the role of osteoprotegerin as a marker of breast cancer risk among women with a BRCA1 mutation

Women with a pathogenic germline mutation in the BRCA1 gene face a very high lifetime risk of developing breast cancer, estimated at 72% by age 80. Prophylactic bilateral mastectomy is the only effective way to lower their risk; however, most women with a mutation opt for intensive screening with an...

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Detalles Bibliográficos
Autores principales: Park, Sarah Sohyun, Uzelac, Aleksandra, Kotsopoulos, Joanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9008947/
https://www.ncbi.nlm.nih.gov/pubmed/35418083
http://dx.doi.org/10.1186/s13053-022-00223-3