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Pyruvate kinase, a metabolic sensor powering glycolysis, drives the metabolic control of DNA replication

BACKGROUND: In all living organisms, DNA replication is exquisitely regulated in a wide range of growth conditions to achieve timely and accurate genome duplication prior to cell division. Failures in this regulation cause DNA damage with potentially disastrous consequences for cell viability and hu...

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Detalles Bibliográficos
Autores principales: Horemans, Steff, Pitoulias, Matthaios, Holland, Alexandria, Pateau, Emilie, Lechaplais, Christophe, Ekaterina, Dariy, Perret, Alain, Soultanas, Panos, Janniere, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009071/
https://www.ncbi.nlm.nih.gov/pubmed/35418203
http://dx.doi.org/10.1186/s12915-022-01278-3