AAV‐mediated expression of secreted and transmembrane αKlotho isoforms rescues relevant aging hallmarks in senescent SAMP8 mice

Senescence represents a stage in life associated with elevated incidence of morbidity and increased risk of mortality due to the accumulation of molecular alterations and tissue dysfunction, promoting a decrease in the organism's protective systems. Thus, aging presents molecular and biological...

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Detalles Bibliográficos
Autores principales: Roig‐Soriano, J., Griñán‐Ferré, C., Espinosa‐Parrilla, J. F., Abraham, C. R., Bosch, A., Pallàs, M., Chillón, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009104/
https://www.ncbi.nlm.nih.gov/pubmed/35274439
http://dx.doi.org/10.1111/acel.13581

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009104/
https://www.ncbi.nlm.nih.gov/pubmed/35274439
http://dx.doi.org/10.1111/acel.13581

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