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AAV‐mediated expression of secreted and transmembrane αKlotho isoforms rescues relevant aging hallmarks in senescent SAMP8 mice
Senescence represents a stage in life associated with elevated incidence of morbidity and increased risk of mortality due to the accumulation of molecular alterations and tissue dysfunction, promoting a decrease in the organism's protective systems. Thus, aging presents molecular and biological...
Autores principales: | Roig‐Soriano, J., Griñán‐Ferré, C., Espinosa‐Parrilla, J. F., Abraham, C. R., Bosch, A., Pallàs, M., Chillón, Miguel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009104/ https://www.ncbi.nlm.nih.gov/pubmed/35274439 http://dx.doi.org/10.1111/acel.13581 |
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