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Temporal and brain region‐specific elevations of soluble Amyloid‐β(40‐42) in the Ts65Dn mouse model of Down syndrome and Alzheimer’s disease

Down syndrome (DS) is a leading cause of intellectual disability that also results in hallmark Alzheimer's disease (AD) pathologies such as amyloid beta (Aβ) plaques and hyperphosphorylated tau. The Ts65Dn mouse model is commonly used to study DS, as trisomic Ts65Dn mice carry 2/3 of the tripli...

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Detalles Bibliográficos
Autores principales:	Tallino, Savannah, Winslow, Wendy, Bartholomew, Samantha K., Velazquez, Ramon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009111/ https://www.ncbi.nlm.nih.gov/pubmed/35290711 http://dx.doi.org/10.1111/acel.13590

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