Organelle dysfunction upon asrij depletion causes aging‐like changes in mouse hematopoietic stem cells

Aging of the blood system is characterized by increased hematopoietic stem cells (HSCs) and myeloid‐biased differentiation leading to higher propensity for hematological malignancies. Unraveling cell‐intrinsic mechanisms regulating HSC aging could aid reversal or slowing of aging. Asrij/OCIAD1 is an...

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Detalles Bibliográficos
Autores principales: Sinha, Saloni, Sinha, Alice, Dongre, Prathamesh, Kamat, Kajal, Inamdar, Maneesha S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Short Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009118/
https://www.ncbi.nlm.nih.gov/pubmed/35289070
http://dx.doi.org/10.1111/acel.13570

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009118/
https://www.ncbi.nlm.nih.gov/pubmed/35289070
http://dx.doi.org/10.1111/acel.13570

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