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Organelle dysfunction upon asrij depletion causes aging‐like changes in mouse hematopoietic stem cells
Aging of the blood system is characterized by increased hematopoietic stem cells (HSCs) and myeloid‐biased differentiation leading to higher propensity for hematological malignancies. Unraveling cell‐intrinsic mechanisms regulating HSC aging could aid reversal or slowing of aging. Asrij/OCIAD1 is an...
Autores principales: | Sinha, Saloni, Sinha, Alice, Dongre, Prathamesh, Kamat, Kajal, Inamdar, Maneesha S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009118/ https://www.ncbi.nlm.nih.gov/pubmed/35289070 http://dx.doi.org/10.1111/acel.13570 |
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