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Enhanced Immune Responses in Mice Induced by the c-di-GMP Adjuvanted Inactivated Vaccine for Pseudorabies Virus

Cyclic dimeric guanosine monophosphate (c-di-GMP) is a bacterial second messenger with immunomodulatory activities in mice, suggesting potential applications as a vaccine immunopotentiator or therapeutic agent. In this study, we evaluated the efficacy of c-di-GMP as an immunopotentiator for pseudora...

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Detalles Bibliográficos
Autores principales: Hou, Liting, Yu, Xiaoming, Zhang, Yuanyuan, Du, Luping, Zhang, Yuanpeng, Cheng, Haiwei, Zheng, Qisheng, Chen, Jin, Hou, Jibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009373/
https://www.ncbi.nlm.nih.gov/pubmed/35432301
http://dx.doi.org/10.3389/fimmu.2022.845680