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Proteomics Challenges for the Assessment of Synuclein Proteoforms as Clinical Biomarkers in Parkinson’s Disease

Parkinson’s disease is a complex neurodegenerative disorder resulting in a multifaceted clinical presentation which includes bradykinesia combined with either rest tremor, rigidity, or both, as well as many non-motor symptoms. The motor features of the disorder are associated with the pathological f...

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Detalles Bibliográficos
Autores principales: Pons, Marie-Laure, Loftus, Neil, Vialaret, Jerome, Moreau, Stephane, Lehmann, Sylvain, Hirtz, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009522/
https://www.ncbi.nlm.nih.gov/pubmed/35431896
http://dx.doi.org/10.3389/fnagi.2022.818606