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Investigating the disordered regions (MoRFs, SLiMs and LCRs) and functions of mimicry proteins/peptides in silico

Microbial mimicry of the host proteins/peptides can elicit host auto-reactive T- or B-cells resulting in autoimmune disease(s). Since intrinsically disordered protein regions (IDPRs) are involved in several host cell signaling and PPI networks, molecular mimicry of the IDPRs can help the pathogens i...

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Detalles Bibliográficos
Autores principales: Garg, Anjali, Dabburu, Govinda Rao, Singhal, Neelja, Kumar, Manish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009644/
https://www.ncbi.nlm.nih.gov/pubmed/35421114
http://dx.doi.org/10.1371/journal.pone.0265657