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SUITOR: Selecting the number of mutational signatures through cross-validation

For de novo mutational signature analysis, the critical first step is to decide how many signatures should be expected in a cancer genomics study. An incorrect number could mislead downstream analyses. Here we present SUITOR (Selecting the nUmber of mutatIonal signaTures thrOugh cRoss-validation), a...

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Detalles Bibliográficos
Autores principales: Lee, Donghyuk, Wang, Difei, Yang, Xiaohong R., Shi, Jianxin, Landi, Maria Teresa, Zhu, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009674/
https://www.ncbi.nlm.nih.gov/pubmed/35377867
http://dx.doi.org/10.1371/journal.pcbi.1009309