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The chromatin remodeling protein CHD-1 and the EFL-1/DPL-1 transcription factor cooperatively down regulate CDK-2 to control SAS-6 levels and centriole number

Centrioles are submicron-scale, barrel-shaped organelles typically found in pairs, and play important roles in ciliogenesis and bipolar spindle assembly. In general, successful execution of centriole-dependent processes is highly reliant on the ability of the cell to stringently control centriole nu...

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Detalles Bibliográficos
Autores principales: Iyer, Jyoti, Gentry, Lindsey K., Bergwell, Mary, Smith, Amy, Guagliardo, Sarah, Kropp, Peter A., Sankaralingam, Prabhu, Liu, Yan, Spooner, Eric, Bowerman, Bruce, O’Connell, Kevin F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009770/
https://www.ncbi.nlm.nih.gov/pubmed/35377871
http://dx.doi.org/10.1371/journal.pgen.1009799