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The spindle assembly checkpoint and the spatial activation of Polo kinase determine the duration of cell division and prevent tumor formation

The maintenance of a restricted pool of asymmetrically dividing stem cells is essential for tissue homeostasis. This process requires the control of mitotic progression that ensures the accurate chromosome segregation. In addition, this event is coupled to the asymmetric distribution of cell fate de...

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Detalles Bibliográficos
Autores principales: Gallaud, Emmanuel, Richard-Parpaillon, Laurent, Bataillé, Laetitia, Pascal, Aude, Métivier, Mathieu, Archambault, Vincent, Giet, Régis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009772/
https://www.ncbi.nlm.nih.gov/pubmed/35377889
http://dx.doi.org/10.1371/journal.pgen.1010145