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The spindle assembly checkpoint and the spatial activation of Polo kinase determine the duration of cell division and prevent tumor formation
The maintenance of a restricted pool of asymmetrically dividing stem cells is essential for tissue homeostasis. This process requires the control of mitotic progression that ensures the accurate chromosome segregation. In addition, this event is coupled to the asymmetric distribution of cell fate de...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009772/ https://www.ncbi.nlm.nih.gov/pubmed/35377889 http://dx.doi.org/10.1371/journal.pgen.1010145 |