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Determining clinically relevant features in cytometry data using persistent homology

Cytometry experiments yield high-dimensional point cloud data that is difficult to interpret manually. Boolean gating techniques coupled with comparisons of relative abundances of cellular subsets is the current standard for cytometry data analysis. However, this approach is unable to capture more s...

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Detalles Bibliográficos
Autores principales: Mukherjee, Soham, Wethington, Darren, Dey, Tamal K., Das, Jayajit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009779/
https://www.ncbi.nlm.nih.gov/pubmed/35312683
http://dx.doi.org/10.1371/journal.pcbi.1009931