Cell-directed aptamer therapeutic targeting for cancers including those within the central nervous system

Osteopontin (OPN) is produced by tumor cells as well as by myeloid cells and is enriched in the tumor microenvironment (TME) of many cancers. Given the roles of OPN in tumor progression and immune suppression, we hypothesized that targeting OPN with aptamers that have high affinity and specificity c...

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Detalles Bibliográficos
Autores principales: Wei, Jun, Song, Renduo, Sabbagh, Aria, Marisetty, Anantha, Shukla, Neal, Fang, Dexing, Najem, Hinda, Ott, Martina, Long, James, Zhai, Lijie, Lesniak, Maciej S., James, Charles David, Platanias, Leonidas, Curran, Michael, Heimberger, Amy B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009928/
https://www.ncbi.nlm.nih.gov/pubmed/35433114
http://dx.doi.org/10.1080/2162402X.2022.2062827

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009928/
https://www.ncbi.nlm.nih.gov/pubmed/35433114
http://dx.doi.org/10.1080/2162402X.2022.2062827

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