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FKBP51 Contributes to Uterine Leiomyoma Pathogenesis by Inducing Cell Proliferation and Extracellular Matrix Deposition

The FK506-binding protein 51 (FKBP51) binds progesterone receptor (PR), glucocorticoid receptor (GR), and androgen receptor (AR) to coregulate their transcriptional activity. We evaluated FKBP51 expression and function in human leiomyoma vs. myometrial tissues and primary cultures to discover FKBP51...

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Detalles Bibliográficos
Autores principales: New, Erika P., Semerci, Nihan, Ozmen, Asli, Guo, Xiaofang, Jonnalagadda, Venkata A., Kim, Joung Woul, Anderson, Matthew L., Guzeloglu-Kayisli, Ozlem, Imudia, Anthony N., Lockwood, Charles J., Kayisli, Umit A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009985/
https://www.ncbi.nlm.nih.gov/pubmed/35426036
http://dx.doi.org/10.1007/s43032-022-00921-2