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FKBP51 Contributes to Uterine Leiomyoma Pathogenesis by Inducing Cell Proliferation and Extracellular Matrix Deposition
The FK506-binding protein 51 (FKBP51) binds progesterone receptor (PR), glucocorticoid receptor (GR), and androgen receptor (AR) to coregulate their transcriptional activity. We evaluated FKBP51 expression and function in human leiomyoma vs. myometrial tissues and primary cultures to discover FKBP51...
Autores principales: | New, Erika P., Semerci, Nihan, Ozmen, Asli, Guo, Xiaofang, Jonnalagadda, Venkata A., Kim, Joung Woul, Anderson, Matthew L., Guzeloglu-Kayisli, Ozlem, Imudia, Anthony N., Lockwood, Charles J., Kayisli, Umit A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009985/ https://www.ncbi.nlm.nih.gov/pubmed/35426036 http://dx.doi.org/10.1007/s43032-022-00921-2 |
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