In Vitro Characterization of (177)Lu-DOTA-M5A Anti-Carcinoembryonic Antigen Humanized Antibody and HSP90 Inhibition for Potentiated Radioimmunotherapy of Colorectal Cancer

Carcinoembryonic antigen (CEA) is an antigen that is highly expressed in colorectal cancers and widely used as a tumor marker. (131)I and (90)Y-radiolabeled anti-CEA monoclonal antibodies (mAbs) have previously been assessed for radioimmunotherapy in early clinical trials with promising results. Mor...

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Detalles Bibliográficos
Autores principales: Mohajershojai, Tabassom, Jha, Preeti, Boström, Anna, Frejd, Fredrik Y., Yazaki, Paul J., Nestor, Marika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010075/
https://www.ncbi.nlm.nih.gov/pubmed/35433442
http://dx.doi.org/10.3389/fonc.2022.849338

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010075/
https://www.ncbi.nlm.nih.gov/pubmed/35433442
http://dx.doi.org/10.3389/fonc.2022.849338

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