A Simple and Sensitive HPLC-MS/MS Assay for the Quantitation of Blonanserin and N-Desethyl Blonanserin in Rat Plasma and Its Application to Pharmacokinetic Study

A high-performance liquid chromatographic method coupled with triple quadrupole mass spectrometry (LC-MS/MS) for the analysis of blonanserin and its active metabolite, N-desethyl blonanserin, in rat plasma has been developed and validated. The biological samples were treated by simple direct protein...

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Detalles Bibliográficos
Autores principales: Huang, Shan-qing, Li, Xiao-lin, Wang, Zhan-zhang, Lu, Hao-yang, Xiao, Tao, Ni, Xiao-jia, Liu, Shu-jing, Zhang, Ming, Shang, De-wei, Wen, Yu-guan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010218/
https://www.ncbi.nlm.nih.gov/pubmed/35433070
http://dx.doi.org/10.1155/2022/5914581

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010218/
https://www.ncbi.nlm.nih.gov/pubmed/35433070
http://dx.doi.org/10.1155/2022/5914581

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