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Central-to-Folding Chirality Control: Asymmetric Synthesis of Multilayer 3D Targets With Electron-Deficient Bridges

New multilayer 3D chiral molecules have been designed and synthesized asymmetrically through the strategy of center-to-multilayer folding chirality control and double Suzuki couplings. Individual diastereoisomers were readily obtained and separated via flash column chromatography. The key diastereoi...

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Detalles Bibliográficos
Autores principales: Jin, Shengzhou, Wang, Jia-Ying, Tang, Yao, Rouh, Hossein, Zhang, Sai, Xu, Ting, Wang, Yu, Yuan, Qingkai, Chen, Daixiang, Unruh, Daniel, Li, Guigen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010227/
https://www.ncbi.nlm.nih.gov/pubmed/35433628
http://dx.doi.org/10.3389/fchem.2022.860398