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Effect of food on capsule and granule formulations of selumetinib

Selumetinib is an oral, potent, and highly selective allosteric MEK1/2 inhibitor approved for the treatment of pediatric patients (aged ≥2 years) with neurofibromatosis type 1 who have symptomatic, inoperable plexiform neurofibromas. A granule formulation of selumetinib is under development to impro...

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Detalles Bibliográficos
Autores principales: Cohen‐Rabbie, Sarit, Mattinson, Alexandra, So, Karen, Wang, Nan, Goldwater, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010250/
https://www.ncbi.nlm.nih.gov/pubmed/35170228
http://dx.doi.org/10.1111/cts.13209