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Structures of Omicron spike complexes and implications for neutralizing antibody development

The emergence of the SARS-CoV-2 Omicron variant is dominant in many countries worldwide. The high number of spike mutations is responsible for the broad immune evasion from existing vaccines and antibody drugs. To understand this, we first present the cryo-electron microscopy structure of ACE2-bound...

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Detalles Bibliográficos
Autores principales: Guo, Hangtian, Gao, Yan, Li, Tinghan, Li, Tingting, Lu, Yuchi, Zheng, Le, Liu, Yue, Yang, Tingting, Luo, Feiyang, Song, Shuyi, Wang, Wei, Yang, Xiuna, Nguyen, Henry C., Zhang, Hongkai, Huang, Ailong, Jin, Aishun, Yang, Haitao, Rao, Zihe, Ji, Xiaoyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010281/
https://www.ncbi.nlm.nih.gov/pubmed/35477022
http://dx.doi.org/10.1016/j.celrep.2022.110770