Loss of IRF7 accelerates acute myeloid leukemia progression and induces VCAM1-VLA-4 mediated intracerebral invasion

Interferon regulatory factor 7 (IRF7) is widely studied in inflammatory models. Its effects on malignant progression have been documented mainly from the perspective of the microenvironment. However, its role in leukemia has not been established. Here we used MLL-AF9-induced acute myeloid leukemia (...

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Detalles Bibliográficos
Autores principales: Wang, Hao, Zhang, Dongyue, Cui, Xiaoxi, Dai, Yibo, Wang, Chenchen, Feng, Wenli, Lv, Xiaoqian, Li, Yifei, Wang, Lina, Ru, Yongxin, Zhang, Yingchi, Ren, Qian, Zheng, Guoguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010288/
https://www.ncbi.nlm.nih.gov/pubmed/35256780
http://dx.doi.org/10.1038/s41388-022-02233-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010288/
https://www.ncbi.nlm.nih.gov/pubmed/35256780
http://dx.doi.org/10.1038/s41388-022-02233-w

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