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Lack of TRPV1 aggravates obesity-associated hypertension through the disturbance of mitochondrial Ca2+ homeostasis in brown adipose tissue

The combination of obesity and hypertension is associated with high morbidity and mortality; however, the mechanism underlying obesity-induced hypertension remains unclear. In this study, we detected the possible effects of TRPV1, a previously identified antihypertensive calcium (Ca(2+)) channel in...

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Detalles Bibliográficos
Autores principales: Li, Li, Ma, Liqun, Luo, Zhidan, Wei, Xiao, Zhao, Yu, Zhou, Cui, Mou, Aidi, Lu, Zongshi, You, Mei, He, Chengkang, Ma, Huan, Zhou, Qing, Wang, Lijuan, Cao, Tingbing, Gu, Yucun, Gao, Peng, Zhu, Zhiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010289/
https://www.ncbi.nlm.nih.gov/pubmed/35043013
http://dx.doi.org/10.1038/s41440-021-00842-8