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Bound nucleotide can control the dynamic architecture of monomeric actin

Polymerization of actin into cytoskeletal filaments is coupled to its bound adenine nucleotides. The mechanism by which nucleotide modulates actin functions has not been evident from analyses of ATP- and ADP-bound crystal structures of the actin monomer. We report that NMR chemical shift differences...

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Detalles Bibliográficos
Autores principales: Ali, Rustam, Zahm, Jacob A., Rosen, Michael K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010300/
https://www.ncbi.nlm.nih.gov/pubmed/35332323
http://dx.doi.org/10.1038/s41594-022-00743-5