DNA is loaded through the 9-1-1 DNA checkpoint clamp in the opposite direction of the PCNA clamp

The 9-1-1 DNA checkpoint clamp is loaded onto 5′-recessed DNA to activate the DNA damage checkpoint that arrests the cell cycle. The 9-1-1 clamp is a heterotrimeric ring that is loaded in Saccharomyces cerevisiae by Rad24-RFC (hRAD17-RFC), an alternate clamp loader in which Rad24 replaces Rfc1 in th...

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Detalles Bibliográficos
Autores principales: Zheng, Fengwei, Georgescu, Roxana E., Yao, Nina Y., O’Donnell, Michael E., Li, Huilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010301/
https://www.ncbi.nlm.nih.gov/pubmed/35314830
http://dx.doi.org/10.1038/s41594-022-00742-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010301/
https://www.ncbi.nlm.nih.gov/pubmed/35314830
http://dx.doi.org/10.1038/s41594-022-00742-6

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