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Short- and long-range interactions in the HIV-1 5′ UTR regulate genome dimerization and packaging

RNA dimerization is the noncovalent association of two human immunodeficiency virus-1 (HIV-1) genomes. It is a conserved step in the HIV-1 life cycle and assumed to be a prerequisite for binding to the viral structural protein Pr55(Gag) during genome packaging. Here, we developed functional analysis...

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Detalles Bibliográficos
Autores principales: Ye, Liqing, Gribling-Burrer, Anne-Sophie, Bohn, Patrick, Kibe, Anuja, Börtlein, Charlene, Ambi, Uddhav B., Ahmad, Shazeb, Olguin-Nava, Marco, Smith, Maureen, Caliskan, Neva, von Kleist, Max, Smyth, Redmond P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010304/
https://www.ncbi.nlm.nih.gov/pubmed/35347312
http://dx.doi.org/10.1038/s41594-022-00746-2