Genome-wide risk prediction of common diseases across ancestries in one million people

Polygenic risk scores (PRS) measure genetic disease susceptibility by combining risk effects across the genome. For coronary artery disease (CAD), type 2 diabetes (T2D), and breast and prostate cancer, we performed cross-ancestry evaluation of genome-wide PRSs in six biobanks in Europe, the United S...

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Detalles Bibliográficos
Autores principales: Mars, Nina, Kerminen, Sini, Feng, Yen-Chen A., Kanai, Masahiro, Läll, Kristi, Thomas, Laurent F., Skogholt, Anne Heidi, della Briotta Parolo, Pietro, Neale, Benjamin M., Smoller, Jordan W., Gabrielsen, Maiken E., Hveem, Kristian, Mägi, Reedik, Matsuda, Koichi, Okada, Yukinori, Pirinen, Matti, Palotie, Aarno, Ganna, Andrea, Martin, Alicia R., Ripatti, Samuli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Short Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010308/
https://www.ncbi.nlm.nih.gov/pubmed/35591975
http://dx.doi.org/10.1016/j.xgen.2022.100118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010308/
https://www.ncbi.nlm.nih.gov/pubmed/35591975
http://dx.doi.org/10.1016/j.xgen.2022.100118

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