Identifying phenotype-associated subpopulations by integrating bulk and single-cell sequencing data

Single-cell RNA sequencing distinguishes cell types, states, and lineages within the context of heterogeneous tissues. However current single-cell data cannot directly link cell clusters with specific phenotypes. Here we present Scissor, a method that identifies cell subpopulations from single-cell...

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Detalles Bibliográficos
Autores principales: Sun, Duanchen, Guan, Xiangnan, Moran, Amy E., Wu, Ling-Yun, Qian, David Z., Schedin, Pepper, Dai, Mu-Shui, Danilov, Alexey V., Alumkal, Joshi J., Adey, Andrew C., Spellman, Paul T., Xia, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010342/
https://www.ncbi.nlm.nih.gov/pubmed/34764492
http://dx.doi.org/10.1038/s41587-021-01091-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010342/
https://www.ncbi.nlm.nih.gov/pubmed/34764492
http://dx.doi.org/10.1038/s41587-021-01091-3

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