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Divalent magnesium restores cytoskeletal storage lesions in cold-stored platelet concentrates

Cold storage of platelet concentrates (PC) has become attractive due to the reduced risk of bacterial proliferation, but in vivo circulation time of cold-stored platelets is reduced. Ca(2+) release from storage organelles and higher activity of Ca(2+) pumps at temperatures < 15 °C triggers cytosk...

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Detalles Bibliográficos
Autores principales: Aurich, Konstanze, Wesche, Jan, Ulbricht, Martin, Otto, Oliver, Greinacher, Andreas, Palankar, Raghavendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010418/
https://www.ncbi.nlm.nih.gov/pubmed/35422472
http://dx.doi.org/10.1038/s41598-022-10231-x