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Impact of chosen cutoff on response rate differences between selective serotonin reuptake inhibitors and placebo
Response defined as a 50% reduction in the sum score of the Hamilton Depression Rating Scale (HDRS-17-sum) is often used to assess the efficacy of antidepressants. Critics have, however, argued that dichotomising ratings with a cutoff close to the median may lead to scores clustering on either side,...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010419/ https://www.ncbi.nlm.nih.gov/pubmed/35422023 http://dx.doi.org/10.1038/s41398-022-01882-5 |