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Impact of chosen cutoff on response rate differences between selective serotonin reuptake inhibitors and placebo

Response defined as a 50% reduction in the sum score of the Hamilton Depression Rating Scale (HDRS-17-sum) is often used to assess the efficacy of antidepressants. Critics have, however, argued that dichotomising ratings with a cutoff close to the median may lead to scores clustering on either side,...

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Detalles Bibliográficos
Autores principales: Lisinski, Alexander, Hieronymus, Fredrik, Nilsson, Staffan, Eriksson, Elias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010419/
https://www.ncbi.nlm.nih.gov/pubmed/35422023
http://dx.doi.org/10.1038/s41398-022-01882-5