Cargando…
Impact of chosen cutoff on response rate differences between selective serotonin reuptake inhibitors and placebo
Response defined as a 50% reduction in the sum score of the Hamilton Depression Rating Scale (HDRS-17-sum) is often used to assess the efficacy of antidepressants. Critics have, however, argued that dichotomising ratings with a cutoff close to the median may lead to scores clustering on either side,...
Autores principales: | Lisinski, Alexander, Hieronymus, Fredrik, Nilsson, Staffan, Eriksson, Elias |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010419/ https://www.ncbi.nlm.nih.gov/pubmed/35422023 http://dx.doi.org/10.1038/s41398-022-01882-5 |
Ejemplares similares
-
The complex clinical response to selective serotonin reuptake inhibitors in depression: a network perspective
por: Boschloo, Lynn, et al.
Publicado: (2023) -
Consistent superiority of selective serotonin reuptake inhibitors over placebo in reducing depressed mood in patients with major depression
por: Hieronymus, F, et al.
Publicado: (2016) -
Item-based analysis of the effects of duloxetine in depression: a patient-level post hoc study
por: Lisinski, Alexander, et al.
Publicado: (2019) -
Expression of 22 serotonin-related genes in rat brain after sub-acute serotonin depletion or reuptake inhibition
por: Näslund, Jakob, et al.
Publicado: (2020) -
A mega-analysis of fixed-dose trials reveals dose-dependency and a rapid onset of action for the antidepressant effect of three selective serotonin reuptake inhibitors
por: Hieronymus, F, et al.
Publicado: (2016)