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Hidden information on protein function in censuses of proteome foldedness
Methods that assay protein foldedness with proteomics have generated censuses of apparent protein folding stabilities in biological milieu. However, different censuses poorly correlate with each other. Here, we show that the reason for this is that methods targeting foldedness through monitoring ami...
Autores principales: | Cox, Dezerae, Ang, Ching-Seng, Nillegoda, Nadinath B., Reid, Gavin E., Hatters, Danny M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010426/ https://www.ncbi.nlm.nih.gov/pubmed/35422070 http://dx.doi.org/10.1038/s41467-022-29661-2 |
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