MLKL deficiency in Braf(V600E)Pten(−/−) melanoma model results in a modest delay of nevi development and reduced lymph node dissemination in male mice

Cancers acquire several capabilities to survive the multistep process in carcinogenesis. Resisting cell death is one of them. Silencing of the necroptosis initiator Ripk3 occurs in a wide variety of cancer types including melanoma. Little is known about the role of the necroptosis executioner MLKL i...

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Detalles Bibliográficos
Autores principales: Martens, Sofie, Takahashi, Nozomi, Blancke, Gillian, Vandamme, Niels, Verschuere, Hanne, Divert, Tatyana, Vuylsteke, Marnik, Berx, Geert, Vandenabeele, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010476/
https://www.ncbi.nlm.nih.gov/pubmed/35422482
http://dx.doi.org/10.1038/s41419-022-04819-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010476/
https://www.ncbi.nlm.nih.gov/pubmed/35422482
http://dx.doi.org/10.1038/s41419-022-04819-4

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