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Co-treatment with Esculin and erythropoietin protects against renal ischemia–reperfusion injury via P2X7 receptor inhibition and PI3K/Akt activation

Renal ischemia/reperfusion (RI/R) is a critical clinical outcome with slightly reported improvement in mortality and morbidity. Effective therapies are still crucially required. Accordingly, the therapeutic effects of esculin (ESC, LCESI-MS/MS-isolated compound from Vachellia farnesiana flowers extr...

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Detalles Bibliográficos
Autores principales: El-Maadawy, Walaa H., Hassan, Marwa, Hafiz, Ehab, Badawy, Mohamed H., Eldahshan, Samir, AbuSeada, AbdulRahman, El-Shazly, Maha A. M., Ghareeb, Mosad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010483/
https://www.ncbi.nlm.nih.gov/pubmed/35422072
http://dx.doi.org/10.1038/s41598-022-09970-8