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Mitochondrial Respiratory Chain Dysfunction—A Hallmark Pathology of Idiopathic Parkinson’s Disease?

Parkinson’s disease (PD) is the most common age-dependent neurodegenerative synucleinopathy. Loss of dopaminergic neurons of the substantia nigra pars compacta, together with region- and cell-specific aggregations of [Formula: see text] -synuclein are considered main pathological hallmarks of PD, bu...

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Detalles Bibliográficos
Autores principales: Flønes, Irene H., Tzoulis, Charalampos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010539/
https://www.ncbi.nlm.nih.gov/pubmed/35433702
http://dx.doi.org/10.3389/fcell.2022.874596