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Reactive oxygen species (ROS)-responsive size-reducible nanoassemblies for deeper atherosclerotic plaque penetration and enhanced macrophage-targeted drug delivery

Nanoparticle-based therapeutics represent potential strategies for treating atherosclerosis; however, the complex plaque microenvironment poses a barrier for nanoparticles to target the dysfunctional cells. Here, we report reactive oxygen species (ROS)-responsive and size-reducible nanoassemblies, f...

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Detalles Bibliográficos
Autores principales: He, Jianhua, Zhang, Wenli, Zhou, Xiaoju, Xu, Fengfei, Zou, Jiahui, Zhang, Qiqi, Zhao, Yi, He, Hongliang, Yang, Hu, Liu, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010555/
https://www.ncbi.nlm.nih.gov/pubmed/35475030
http://dx.doi.org/10.1016/j.bioactmat.2022.03.041