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The non-adrenergic imidazoline-1 receptor protein nischarin is a key regulator of astrocyte glutamate uptake

Astrocytic GLT-1 is the main glutamate transporter involved in glutamate buffering in the brain, pivotal for glutamate removal at excitatory synapses to terminate neurotransmission and for preventing excitotoxicity. We show here that the surface expression and function of GLT-1 can be rapidly modula...

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Detalles Bibliográficos
Autores principales: Gupta, Swati, Bazargani, Narges, Drew, James, Howden, Jack H., Modi, Souvik, Al Awabdh, Sana, Marie, Hélène, Attwell, David, Kittler, Josef T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010640/
https://www.ncbi.nlm.nih.gov/pubmed/35434559
http://dx.doi.org/10.1016/j.isci.2022.104127