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A dual SHOX2:GFP; MYH6:mCherry knockin hESC reporter line for derivation of human SAN-like cells

The sinoatrial node (SAN) is the primary pacemaker of the heart. The human SAN is poorly understood due to limited primary tissue access and limitations in robust in vitro derivation methods. We developed a dual SHOX2:GFP; MYH6:mCherry knockin human embryonic stem cell (hESC) reporter line, which al...

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Detalles Bibliográficos
Autores principales: Ghazizadeh, Zaniar, Zhu, Jiajun, Fattahi, Faranak, Tang, Alice, Sun, Xiaolu, Amin, Sadaf, Tsai, Su-Yi, Khalaj, Mona, Zhou, Ting, Samuel, Ryan M., Zhang, Tuo, Ortega, Francis A., Gordillo, Miriam, Moroziewicz, Dorota, Paull, Daniel, Noggle, Scott A., Xiang, Jenny Zhaoying, Studer, Lorenz, Christini, David J., Pitt, Geoffrey S., Evans, Todd, Chen, Shuibing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010642/
https://www.ncbi.nlm.nih.gov/pubmed/35434558
http://dx.doi.org/10.1016/j.isci.2022.104153