A Novel Porcine Model of Ischemia-Reperfusion Injury After Cross-Clamping the Thoracic Aorta Revealed Substantial Cardiopulmonary, Thromboinflammatory and Biochemical Changes Without Effect of C1-Inhibitor Treatment

Ischemic injury worsens upon return of blood and innate immunity including the complement system play a central role in ischemia-reperfusion injury (IRI) as in thoracic aortic surgery. Complement component1 inhibitor (C1-INH) has been shown to reduce IRI and is a broad-acting plasma cascade inhibito...

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Detalles Bibliográficos
Autores principales: Nielsen, Erik Waage, Miller, Yoav, Brekke, Ole-Lars, Grond, Joost, Duong, Anh Hoang, Fure, Hilde, Ludviksen, Judith Krey, Pettersen, Kristin, Reubsaet, Leon, Solberg, Rigmor, Johansen, Harald Thidemann, Mollnes, Tom Eirik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010742/
https://www.ncbi.nlm.nih.gov/pubmed/35432333
http://dx.doi.org/10.3389/fimmu.2022.852119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010742/
https://www.ncbi.nlm.nih.gov/pubmed/35432333
http://dx.doi.org/10.3389/fimmu.2022.852119

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