Combined growth hormone and insulin-like growth factor-1 rescues growth retardation in glucocorticoid-treated mdxmice but does not prevent osteopenia

Short stature and osteoporosis are common in Duchenne muscular dystrophy (DMD) and its pathophysiology may include an abnormality of the growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis, which is further exacerbated by long-term glucocorticoid (GC) treatment. Hence, an agent that has anab...

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Detalles Bibliográficos
Autores principales: Wood, Claire L, van ‘t Hof, Rob, Dillon, Scott, Straub, Volker, Wong, Sze C, Ahmed, S Faisal, Farquharson, Colin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010817/
https://www.ncbi.nlm.nih.gov/pubmed/35191394
http://dx.doi.org/10.1530/JOE-21-0388

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010817/
https://www.ncbi.nlm.nih.gov/pubmed/35191394
http://dx.doi.org/10.1530/JOE-21-0388

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