Generation and Characterization of iPS Cells Derived from APECED Patients for Gene Correction

APECED (Autoimmune-Polyendocrinopathy-Candidiasis-Ectodermal-Dystrophy) is a severe and incurable multiorgan autoimmune disease caused by mutations in the AIRE (autoimmune regulator) gene. Without functional AIRE, the development of central and peripheral immune tolerance is severely impaired allowi...

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Detalles Bibliográficos
Autores principales: Karvonen, Eira, Krohn, Kai J. E., Ranki, Annamari, Hau, Annika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010864/
https://www.ncbi.nlm.nih.gov/pubmed/35432216
http://dx.doi.org/10.3389/fendo.2022.794327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010864/
https://www.ncbi.nlm.nih.gov/pubmed/35432216
http://dx.doi.org/10.3389/fendo.2022.794327

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